The GNA13 Polyclonal Antibody (CAB21338) is a valuable tool for researchers studying GNA13, a protein involved in cell signaling processes. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GNA13 protein, this antibody allows for the detection and analysis of GNA13 in a variety of cell types, making it an ideal choice for studies in cell biology and signal transduction research.
GNA13 is a critical regulator of cell proliferation, migration, and survival, playing a key role in various cellular processes such as vascular development and cancer progression. Understanding the function of GNA13 is essential for unraveling its role in diseases like cancer and cardiovascular disorders. By targeting GNA13 with this antibody, researchers can gain insights into its mechanisms of action and potential therapeutic applications in the treatment of these diseases.
Product Name:
GNA13 Polyclonal Antibody
SKU:
CAB21338
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GNA13 (NP_006563.2).
Predicted to enable D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in several processes, including Rho protein signal transduction; activation of phospholipase D activity; and multicellular organism aging. Predicted to act upstream of or within several processes, including branching involved in blood vessel morphogenesis; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
10672
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GNA13 Rabbit pAb (CAB21338) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
