GNA11 Polyclonal Antibody (CAB19313)
- SKU:
- CAB19313
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
Product Name: | GNA11 Polyclonal Antibody |
SKU: | CAB19313 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human GNA11 (NP_002058.2). |
Sequence: | ESKA LFRT IITY PWFQ NSSV ILFL NKKD LLED KILY SHLV DYFP EFDG PQRD AQAA REFI LKMF VDLN PDSD KIIY SHFT CATD TENI RFVF AAVK DTIL Q |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | FBH; FBH2; FHH2; HG1K; HHC2; GNA-11; HYPOC2; GNA11 |
Positive Sample: | BxPC-3,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Lipid-anchor. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
Purification Method: | Affinity purification |
Gene ID: | 2767 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |