GMPS Rabbit Polyclonal Antibody (CAB6606)
- SKU:
- CAB6606
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GMPS Rabbit Polyclonal Antibody |
SKU: | CAB6606 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS (NP_003866.1). |
Sequence: | DTEL IRKL REEG KVIE PLKD FHKD EVRI LGRE LGLP EELV SRHP FPGP GLAI RVIC AEEP YICK DFPE TNNI LKIV ADFS ASVK KPHT LLQR VKAC TTEE DQEK LMQI TSLH SLNA FLLP IKTV GVQG DCRS YSYV CGIS SKDE PDWE SLIF LARL IPRM CHNV NRVV YIFG PPVK EPPT DVTP TFLT TGVL STLR QADF EAHN ILRE SGYA GKIS QMPV ILTP LHFD RDPL QKQP SCQR SVVI RTFI TSDF MTGI PATP GNEI PVEV VLKM VTEI KKIP GISR IMYD LTSK PPGT TEWE |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | GATD7; GMPS |
Positive Sample: | MCF-7,SKOV3,HL-60,U-251MG,Mouse heart,Mouse kidney,Mouse brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 77kDa |
Observed MW: | 80kDa |
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Purification Method: | Affinity purification |
Gene ID: | 8833 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |