The GMPPB Polyclonal Antibody (CAB16520) is a vital tool for researchers studying the GMPPB protein, which plays a crucial role in nucleotide sugar metabolism and protein glycosylation. This antibody, produced using rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GMPPB protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable resource for studies in glycobiology and related fields.GMPPB is a key enzyme involved in the biosynthesis of nucleotide sugars, which serve as building blocks for glycosylation, a post-translational modification essential for protein function.
Dysregulation of GMPPB has been linked to various human diseases, including congenital muscular dystrophy and intellectual disabilities. Through studying the role of GMPPB, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.In summary, the GMPPB Polyclonal Antibody (CAB16520) is a powerful tool for investigating the function and regulation of the GMPPB protein in health and disease. Its high specificity and sensitivity make it an excellent choice for researchers looking to deepen their understanding of nucleotide sugar metabolism and protein glycosylation pathways.
Product Name:
GMPPB Rabbit Polyclonal Antibody
SKU:
CAB16520
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-250 of human GMPPB (NP_068806.1).
This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
29925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GMPPB Rabbit pAb (CAB16520) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
