The GMIP Polyclonal Antibody (CAB17702) is a valuable tool for researchers studying the GMIP protein, which plays a critical role in regulating immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the GMIP protein, this antibody allows for the detection and analysis of GMIP in various cell types, making it ideal for studies in immunology and cancer research.The GMIP protein, also known as GEM-interacting protein, is involved in modulating immune responses and has been linked to diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of GMIP is essential for developing targeted therapies that can manipulate immune function in these disease contexts. The GMIP Polyclonal Antibody provides researchers with a reliable tool for investigating the role of GMIP in immune regulation, offering new insights and potential treatment strategies for a variety of conditions.
Product Name:
GMIP Rabbit Polyclonal Antibody
SKU:
CAB17702
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-91 of human GMIP (NP_057657.2).
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GMIP Rabbit pAb (CAB17702) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
