The GM130 Rabbit Monoclonal Antibody is a highly specific antibody designed for research involving the Golgi Matrix Protein 130 (GM130), a key protein involved in regulating the structure and function of the Golgi apparatus in cells. This monoclonal antibody, produced in rabbits, is optimized for use in various applications such as immunofluorescence, immunohistochemistry, and Western blotting.GM130 is essential for proper Golgi organization and vesicle trafficking, playing a crucial role in intracellular transport and protein glycosylation. Dysregulation of GM130 has been implicated in various human diseases, including cancer and neurodegenerative disorders.
By using the GM130 Rabbit Monoclonal Antibody, researchers can accurately detect and analyze the expression and localization of GM130 in different cell types and tissues, providing valuable insights into its biological functions and potential therapeutic targets. Furthermore, understanding the role of GM130 in cellular processes can lead to the development of new diagnostic tools and targeted treatments for diseases associated with abnormal Golgi function. This antibody is a valuable tool for scientists studying cell biology, cancer biology, and neurobiology, offering high sensitivity and specificity for reliable experimental results.
Product Name:
GM130 Rabbit Monoclonal Antibody
SKU:
CAB11408
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GM130 (Q08379).
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
2801
Clone Number:
ARC0589
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GM130 Rabbit mAb (CAB11408) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
