The Glypican-6 Polyclonal Antibody (CAB2741) is a valuable tool for research on Glypican-6, a member of the glypican family of proteoglycans known for their involvement in cellular signaling and development. This antibody, generated in rabbits, has a high affinity for Glypican-6 in human samples, making it suitable for use in Western blot applications.Glypican-6 is a cell surface protein that plays a role in various cellular processes, including growth factor signaling, cell adhesion, and tissue morphogenesis. Its expression has been linked to conditions such as cancer, developmental disorders, and neurodegenerative diseases, making it a promising target for further investigation.
By utilizing the Glypican-6 Polyclonal Antibody, researchers can effectively study the function and regulation of Glypican-6 in different cell types and tissues. This antibody enables the detection and analysis of Glypican-6 protein levels, providing valuable insights into its role in normal physiology and disease. Overall, the Glypican-6 Polyclonal Antibody is a valuable tool for advancing our understanding of Glypican-6 biology and its potential implications in human health and disease.
Product Name:
GPC6 Rabbit Polyclonal Antibody
SKU:
CAB2741
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-530 of human GPC6 (NP_005699.1).
The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1.
Purification Method:
Affinity purification
Gene ID:
10082
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPC6 antibody (CAB2741) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
