Glypican 3 (GPC3) Rabbit Polyclonal Antibody (CAB1946)
- SKU:
- CAB1946
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Glypican 3 (GPC3) Rabbit Polyclonal Antibody |
SKU: | CAB1946 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 481-580 of human Glypican 3 (GPC3) (NP_004475.1). |
Sequence: | GNSQ QATP KDNE ISTF HN |
Tested Applications: | WB FC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 FC,1:50 - 1:200 |
Synonyms: | SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; Glypican 3 (GPC3) |
Positive Sample: | Mouse lung,Rat kidney,Rat lung ,Hep G2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Secreted, extracellular space. |
Calculated MW: | 66kDa |
Observed MW: | 66kDa |
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2719 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |