Glycophorin C (GYPC) Rabbit Monoclonal Antibody (CAB11472)
The Glycophorin C Rabbit Monoclonal Antibody is a valuable tool for researchers studying the glycophorin C protein, a crucial component of red blood cells. This highly specific antibody, raised in rabbits, is suitable for use in various applications, including Western blot and immunohistochemistry.Glycophorin C is known for its role in maintaining the shape and flexibility of red blood cells, as well as its involvement in certain blood disorders. By targeting this protein, researchers can better understand its function and significance in health and disease.
With its high reactivity and specificity for glycophorin C, this monoclonal antibody is a reliable option for studies in hematology, transfusion medicine, and related fields. Its ability to detect and analyze glycophorin C in different experimental settings makes it a valuable asset for advancing our knowledge of red blood cell biology and associated conditions.
Product Name:
Glycophorin C (GYPC) Rabbit Monoclonal Antibody
SKU:
CAB11472
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 49-128 of human Glycophorin C (GYPC) (P04921).
Cell membrane, Single-pass type III membrane protein.
Calculated MW:
14kDa
Observed MW:
30-40kDa
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2995
Clone Number:
ARC0605
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Glycophorin C (GYPC) Rabbit mAb (CAB11472) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
