Glycophorin C (GYPC) Rabbit Polyclonal Antibody (CAB1232)
The Glycophorin-C Polyclonal Antibody (CAB1232) is a vital tool for researchers studying Glycophorin-C, a cell surface protein involved in red blood cell function and membrane stability. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting Glycophorin-C in human samples, making it an essential reagent for Western blot analysis.Glycophorin-C, a glycoprotein found on the surface of red blood cells, plays a crucial role in maintaining cell shape and stability, as well as mediating cell-cell interactions. Dysregulation of Glycophorin-C expression has been linked to various blood disorders and conditions, making it a target of interest for researchers in hematology and related fields.
By utilizing the Glycophorin-C Polyclonal Antibody, researchers can accurately detect and quantify Glycophorin-C levels in different cell types and tissues, providing valuable insights into its function and potential implications in disease. This antibody is a valuable tool for investigations into red blood cell biology, hematological disorders, and related research areas.
Product Name:
Glycophorin C (GYPC) Rabbit Polyclonal Antibody
SKU:
CAB1232
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human Glycophorin C (Glycophorin C (GYPC)) (NP_002092.1).
Cell membrane, Single-pass type III membrane protein.
Calculated MW:
14kDa
Observed MW:
34kDa
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2995
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Glycophorin C (Glycophorin C (GYPC)) antibody (CAB1232) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
