The Glycerate Kinase Polyclonal Antibody (CAB7852) is a specialized research tool designed for studying glycerate kinase, an essential enzyme involved in the glyoxylate and dicarboxylate metabolism pathway. This antibody, produced in rabbits, exhibits high specificity and reactivity with glycerate kinase in various biological samples, particularly in human tissues.Utilizing this antibody in Western blot applications allows for the accurate detection and analysis of glycerate kinase protein expression levels in different cell types and tissues. Its reliability and performance make it a valuable tool for researchers investigating the metabolic pathways that play a crucial role in various physiological processes.Glycerate kinase is a key enzyme that catalyzes the conversion of glycerate to 2-phosphoglycerate, playing a significant role in energy metabolism and amino acid synthesis.
Dysregulation of glycerate kinase has been implicated in various metabolic disorders and diseases such as cancer, diabetes, and neurological disorders. Therefore, studying the expression and activity of glycerate kinase is essential for gaining insights into the pathophysiology of these conditions and identifying potential therapeutic targets.Overall, the Glycerate Kinase Polyclonal Antibody (CAB7852) provides researchers with a valuable tool for investigating the role of glycerate kinase in metabolic pathways and its potential implications in health and disease.
Product Name:
GLYCTK Rabbit Polyclonal Antibody
SKU:
CAB7852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 284-523 of human GLYCTK (NP_660305.2).
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
132158
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GLYCTK antibody (CAB7852) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
