The GLYATL1 Polyclonal Antibody (PAC043964) is a valuable tool for research focused on GLYATL1, an enzyme involved in the metabolism of glycine, an essential amino acid. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GLYATL1 protein, researchers can detect and analyze its expression in various cell types, making it a versatile option for studies related to metabolism and amino acid processing.
GLYATL1 is a key player in glycine metabolism, contributing to processes like detoxification and neurotransmission. Understanding the function of this enzyme is important for unraveling its role in various metabolic pathways and diseases, such as metabolic disorders, neurodegenerative conditions, and cancer. The GLYATL1 Polyclonal Antibody offers researchers a reliable tool to delve deeper into the mechanisms involving this enzyme and its potential implications in health and disease.
Recombinant Human Glycine N-acyltransferase-like protein 1 protein (1-302AA)
Form:
Liquid
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method:
Antigen Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot. All lanes: GLYATL1 antibody at 8µg/ml + Rat liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36, 39 kDa. Observed band size: 36 kDa.
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO43964 at dilution of 1:100.
Background:
Acyltransferase which transfers an acyl group to the N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor.
Synonyms:
Glycine N-acyltransferase-like protein 1 (EC 2.3.1.68) (Acyl-CoA:glycine N-acyltransferase-like protein 1) (Glutamine N-acyltransferase), GLYATL1, GNAT
UniProt Protein Function:
GLYATL1 iso1: Acyltransferase which transfers an acyl group to the N- terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor. Belongs to the glycine N-acyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.3.1.68; TransferaseChromosomal Location of Human Ortholog: 11q12.1Cellular Component: mitochondrionMolecular Function: glycine N-acyltransferase activity; glutamine N-acyltransferase activityBiological Process: metabolic process
