The GLYAT Polyclonal Antibody (CAB14100) is a crucial tool for researchers studying GLYAT, an important enzyme involved in glycine metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GLYAT protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in metabolic pathways and related diseases.
GLYAT, also known as glycine-N-acyltransferase, plays a vital role in glycine conjugation, a process involved in the detoxification of various compounds in the body. Dysregulation of GLYAT has been linked to metabolic disorders, liver disease, and cancer, making it a promising target for therapeutic interventions. Understanding the function and regulation of GLYAT can provide valuable insights into disease mechanisms and potential treatment strategies.
Product Name:
GLYAT Rabbit Polyclonal Antibody
SKU:
CAB14100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human GLYAT (NP_005829.3).
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10249
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GLYAT Rabbit pAb (CAB14100) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
