The Glutathione Synthetase Rabbit Monoclonal Antibody is a powerful tool for researchers studying glutathione synthesis and its role in cellular health. This antibody, raised in rabbits, has high specificity and sensitivity for detecting the glutathione synthetase protein in various samples. Validated for use in Western blot applications, the antibody provides accurate and reliable results for analyzing glutathione synthetase levels in different cell types.Glutathione is a critical antioxidant that plays a key role in protecting cells from oxidative stress and maintaining overall cellular function.
Glutathione synthetase is the enzyme responsible for synthesizing glutathione, making it an important target for research in fields such as oxidative stress, aging, and diseases related to cellular damage.By using the Glutathione Synthetase Rabbit Monoclonal Antibody, researchers can gain valuable insights into the regulation of glutathione synthesis and its impact on cellular processes. This antibody is an essential tool for studies focusing on oxidative stress, cellular health, and potential therapeutic strategies targeting the glutathione system.
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Purification Method:
Affinity purification
Gene ID:
2937
Clone Number:
ARC0630
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Glutathione Synthetase (GSS) (GSS) Rabbit mAb (CAB11557) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.