GLRX Rabbit Polyclonal Antibody (CAB5315)
- SKU:
- CAB5315
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GLRX Rabbit Polyclonal Antibody |
SKU: | CAB5315 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_002055.1). |
Sequence: | MAQE FVNC KIQP GKVV VFIK PTCP YCRR AQEI LSQL PIKQ GLLE FVDI TATN HTNE IQDY LQQL TGAR TVPR VFIG KDCI GGCS DLVS LQQS GELL TRLK QIGA LQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | GRX; GRX1; GLRX |
Positive Sample: | SW480,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method: | Affinity purification |
Gene ID: | 2745 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |