The Glutaredoxin 1 (GLRX) Monoclonal Antibody is a cutting-edge tool for researchers studying the role of GLRX in cellular processes and disease. GLRX is a key enzyme involved in redox signaling and regulation, playing a critical role in maintaining cellular redox homeostasis.This monoclonal antibody, produced using advanced technology, offers high specificity and sensitivity for detecting GLRX in various samples, including human tissues and cell lines. It is validated for use in Western blot analysis, immunofluorescence, and immunohistochemistry applications, providing researchers with versatile options for their experiments.
With its ability to accurately target and detect GLRX, this antibody is essential for studies on oxidative stress, cancer biology, neurodegenerative diseases, and other conditions where redox regulation is implicated. By understanding the functions and mechanisms of GLRX, researchers can potentially develop novel therapeutic strategies for treating a range of diseases.
Product Name:
Glutaredoxin 1 (GLRX) Monoclonal Antibody
SKU:
CAB23246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 11-106 of human Glutaredoxin 1 (GLRX) (NP_002055.1).
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
2745
Clone Number:
ARC59054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Glutaredoxin 1（GLRX） Rabbit mAb (CAB23246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
