Glutaredoxin 1 (GLRX) Monoclonal Antibody (CAB23246)
- SKU:
- CAB23246
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Glutaredoxin 1 (GLRX) Monoclonal Antibody |
SKU: | CAB23246 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 11-106 of human Glutaredoxin 1 (GLRX) (NP_002055.1). |
Sequence: | QPGK VVVF IKPT CPYC RRAQ EILS QLPI KQGL LEFV DITA TNHT NEIQ DYLQ QLTG ARTV PRVF IGKD CIGG CSDL VSLQ QSGE LLTR LKQI GALQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GRX; GRX1; Glutaredoxin 1 (GLRX) |
Positive Sample: | Jurkat, Mouse liver, Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method: | Affinity purification |
Gene ID: | 2745 |
Clone Number: | ARC59054 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |