The GLUT3 Rabbit Monoclonal Antibody (CAB4137) is a cutting-edge tool for researchers studying glucose transporter 3 (GLUT3), a crucial protein involved in glucose uptake and metabolism. This antibody is produced using rabbit monoclonal technology, ensuring high specificity and sensitivity in detecting GLUT3 expression in various biological samples. GLUT3 is known for its high affinity for glucose and its role in facilitating glucose transport across cell membranes, particularly in tissues with high energy demands such as the brain and red blood cells. Dysregulation of GLUT3 expression has been linked to metabolic disorders, neurodegenerative diseases, and cancer, making it a valuable target for research in these areas.
By utilizing the GLUT3 Rabbit Monoclonal Antibody, researchers can accurately study the expression levels and localization of GLUT3 in different cell types and tissues, providing valuable insights into its functional roles and potential therapeutic applications. This antibody is validated for use in Western blotting, immunohistochemistry, and other techniques, offering versatility and reliability for a wide range of experimental needs in the fields of metabolism, neurobiology, and oncology.
Product Name:
GLUT3/SLC2A3 Rabbit Monoclonal Antibody
SKU:
CAB4137
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT3/SLC2A3 (P11169).
Enables dehydroascorbic acid transmembrane transporter activity; glucose binding activity; and glucose transmembrane transporter activity. Involved in glucose import across plasma membrane and transport across blood-brain barrier. Is integral component of plasma membrane. Biomarker of Alzheimer's disease; acanthosis nigricans; diabetes mellitus; and type 2 diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
6515
Clone Number:
ARC0917
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GLUT3/SLC2A3 Rabbit mAb (CAB4137) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.