The Glut2 Rabbit Monoclonal Antibody is a highly specific tool designed for research involving Glut2, a glucose transporter protein essential for glucose homeostasis in the body. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.Glut2 plays a crucial role in glucose uptake and utilization in tissues such as the liver, pancreas, and intestine. Dysregulation of Glut2 has been implicated in conditions such as diabetes and obesity, making it a target of interest in metabolic research.
The Glut2 Rabbit Monoclonal Antibody enables the detection and analysis of Glut2 expression in different cell types, providing valuable insights into its function and regulation.Researchers in the fields of metabolism, diabetes, and nutritional sciences can benefit from the specificity and reliability of the Glut2 Rabbit Monoclonal Antibody in their studies. By understanding the role of Glut2 in glucose metabolism, researchers can advance our knowledge of metabolic disorders and potentially identify new therapeutic targets for intervention.
Product Name:
GLUT2/SLC2A2 Rabbit Monoclonal Antibody
SKU:
CAB12307
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT2/SLC2A2 (P11168).
This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
6514
Clone Number:
ARC0305
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using GLUT2/SLC2A2 Rabbit mAb (CAB12307) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
