GSR Rabbit Monoclonal Antibody (CAB4566)
- SKU:
- CAB4566
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GSR Rabbit Monoclonal Antibody |
SKU: | CAB4566 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 423-522 of human GSR (P00390). |
Sequence: | TVGL TEDE AIHK YGIE NVKT YSTS FTPM YHAV TKRK TKCV MKMV CANK EEKV VGIH MQGL GCDE MLQG FAVA VKMG ATKA DFDN TVAI HPTS SEEL VTLR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GR; GSRD; HEL-75; HEL-S-122m; GSR |
Positive Sample: | Hep G2,A549,K-562,Mouse liver,Mouse brain,Mouse kidney,Rat lung,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method: | Affinity purification |
Gene ID: | 2936 |
Clone Number: | ARC1034 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |