The GluR Rabbit Monoclonal Antibody (CAB4566) is a specialized tool for researchers studying GluR, a class of glutamate receptors involved in synaptic transmission and plasticity in the brain. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards GluR in various experimental settings, making it a valuable asset for neuroscience research.With its superior performance in applications such as immunofluorescence, immunoprecipitation, and flow cytometry, the GluR Rabbit Monoclonal Antibody (CAB4566) enables precise detection and analysis of GluR expression and localization in neuronal cells. Its reliability and consistency make it an essential reagent for investigating the role of GluR in processes like memory formation, learning, and neuroplasticity.
Given the pivotal role of GluR in neuronal communication and synaptic plasticity, understanding its function and regulation is crucial for unraveling the mechanisms underlying neurological disorders such as Alzheimer's disease, epilepsy, and schizophrenia. By using the GluR Rabbit Monoclonal Antibody (CAB4566), researchers can delve deeper into the complexities of GluR-mediated signaling pathways and pave the way for innovative therapeutic interventions targeting these pathways.
Product Name:
GSR Rabbit Monoclonal Antibody
SKU:
CAB4566
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 423-522 of human GSR (P00390).
Hep G2,A549,K-562,Mouse liver,Mouse brain,Mouse kidney,Rat lung,Rat liver,Rat kidney
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Mitochondrion.
Calculated MW:
56kDa
Observed MW:
56kDa
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method:
Affinity purification
Gene ID:
2936
Clone Number:
ARC1034
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GSR Rabbit mAb (CAB4566) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
