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GLUL Monoclonal Antibody [PAT8D7AT] (CPAB0265)

SKU:
CPAB0265
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1 
Clone:
PAT8D7AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

GLUL Monoclonal Antibody [PAT8D7AT] (CPAB0265)

The GLUL Polyclonal Antibody (CPAB0265) is a valuable tool for researchers studying the enzyme Glutamine Synthetase (GLUL), which plays a critical role in the metabolism of glutamine, an essential amino acid involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.GLUL is a key enzyme in the process of converting glutamate and ammonia into glutamine, a process crucial for maintaining nitrogen balance in the body and supporting various metabolic functions. Dysregulation of GLUL activity has been linked to diseases such as cancer, neurodegenerative disorders, and metabolic disorders, making it an important target for research and potential therapeutic interventions.

By using the GLUL Polyclonal Antibody, researchers can detect and analyze GLUL protein levels in different cell types and tissue samples, providing insights into the enzyme's function and regulation in normal and disease states. This antibody is a valuable tool for studies in biochemistry, cell biology, and molecular biology, shedding light on the role of GLUL in health and disease.

Product Name:GLUL Antibody
Product Sku:CPAB0265
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GLUL mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GLUL amino acids 1-373 purified from Ecoli.
Clone:PAT8D7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:GLUL antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1 
Background:GLUL catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a major source of energy and that takes part in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is expressed during early fetal stages, and has a role in maintaining body pH by removing ammonia from circulation. Mutations in GLUL gene are related with congenital glutamine deficiency.
Synonyms:GLNS, EC 6.3.1.2, EC 4.1.1.15, GLUL, Glutamine Synthetase, GS, Glutamate decarboxylase, Glutamate--ammonia ligase, PIG43, PIG59.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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