The GLUD2 Polyclonal Antibody (CAB6604) is a vital tool for researchers studying the glutamate dehydrogenase 2 (GLUD2) protein, an enzyme involved in the regulation of cellular metabolism and energy production. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for Western blot applications.GLUD2 is known to play a crucial role in the metabolism of glutamate, a key neurotransmitter in the central nervous system. Dysregulation of GLUD2 activity has been implicated in various neurological disorders, making it a target of interest for researchers studying conditions such as epilepsy, Parkinson's disease, and Alzheimer's disease.
By detecting and analyzing the GLUD2 protein in different cell types, the CAB6604 antibody enables researchers to further explore the functions and mechanisms of this enzyme in health and disease. Its application in immunology and neuroscience research makes it an essential tool for advancing our understanding of cellular metabolism and its implications for human health.
Product Name:
GLUD2 Rabbit Polyclonal Antibody
SKU:
CAB6604
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_036216.2).
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
Purification Method:
Affinity purification
Gene ID:
2747
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GLUD2 Rabbit pAb (CAB6604) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
