The GluD1 Rabbit Monoclonal Antibody (CAB5176) is a powerful tool for researchers studying the glutamate receptor delta-1 (GluD1) protein. This antibody, raised in rabbits, is highly specific and sensitive to human samples, and is validated for use in Western blot and immunohistochemistry applications.GluD1 is a key player in the regulation of synaptic plasticity and neuronal development, making it a crucial target for studies in neurobiology and neuroscience. The GluD1 Rabbit Monoclonal Antibody binds to the GluD1 protein, enabling precise detection and analysis in various cell types and tissues.
Its high specificity and sensitivity make it an ideal choice for researchers investigating the role of GluD1 in brain function and neurological disorders.By using the GluD1 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and signaling pathways of GluD1, leading to a better understanding of its role in neurological diseases such as autism, schizophrenia, and epilepsy. This antibody is a reliable tool for advancing research in the field of neuroscience and uncovering new therapeutic targets for brain-related disorders.
Product Name:
GLUD1 Rabbit Monoclonal Antibody
SKU:
CAB5176
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 459-558 of human GLUD1 (P00367).
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Purification Method:
Affinity purification
Gene ID:
2746
Clone Number:
ARC1216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GLUD1 Rabbit mAb (CAB5176) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
