Glucosylceramidase beta (GBA) Rabbit Polyclonal Antibody (CAB8420)
- SKU:
- CAB8420
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Glucosylceramidase beta (GBA) Rabbit Polyclonal Antibody |
SKU: | CAB8420 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2). |
Sequence: | ARPC IPKS FGYS SVVC VCNA TYCD SFDP PTFP ALGT FSRY ESTR SGRR MELS MGPI QANH TGTG LLLT LQPE QKFQ KVKG FGGA MTDA AALN ILAL SPPA QNLL LKSY FSEE GIGY NIIR VPMA SCDF SIRT YTYA DTPD DFQL HNFS LPEE DTKL KIPL IHRA LQLA QRPV SLLA SPWT SPTW LKTN GAVN GKGS LKGQ PGDI YHQT WAR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GBA; GCB; GLUC; Glucosylceramidase beta (GBA) |
Positive Sample: | MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Lumenal side, Lysosome membrane, Peripheral membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2629 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |