GluR4/GluA4/GRIA4 Rabbit Monoclonal Antibody (CAB4593)
- SKU:
- CAB4593
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
Product Name: | GluR4/GluA4/GRIA4 Rabbit Monoclonal Antibody |
SKU: | CAB4593 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-902 of human GluR4/GluA4/GRIA4 (P48058). |
Sequence: | SGSK DKTS ALSL SNVA GVFY ILVG GLGL AMLV ALIE FCYK SRAE AKRM KLTF SEAI RNKA RLSI TGSV GENG RVLT PDCP KAVH TGTA IRQS SGLA VIAS DLP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GLUR4; GLURD; GluA4; GLUR4C; NEDSGA; GluA4-ATD; GluR4/GluA4/GRIA4 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Multi-pass membrane protein, dendrite, postsynaptic cell membrane, synapse. |
Calculated MW: | 101kDa |
Observed MW: | 101kDa |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Purification Method: | Affinity purification |
Gene ID: | 2893 |
Clone Number: | ARC1045 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |