The GLT1D1 Polyclonal Antibody (PACO39018) is a valuable tool for researchers studying GLT1D1, a protein known for its involvement in glutamate transport and regulation of excitatory neurotransmission in the brain. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GLT1D1 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for neurobiology and neuroscience research.GLT1D1, a member of the glutamate transporter family, plays a crucial role in maintaining extracellular glutamate levels within the brain, preventing excitotoxicity and supporting proper neuronal function.
Dysregulation of glutamate transport has been implicated in various neurological disorders, including epilepsy, Alzheimer's disease, and Parkinson's disease, highlighting the importance of studying GLT1D1 in these contexts. By elucidating the function of GLT1D1, researchers can potentially uncover new therapeutic targets and strategies for treating these debilitating conditions.
Antibody Name:
GLT1D1 Antibody (PACO39018)
Antibody SKU:
PACO39018
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Glycosyltransferase 1 domain-containing protein 1 protein (17-152AA)
Immunohistochemistry of paraffin-embedded human bladder cancer using PACO39018 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO39018 at dilution of 1:100.
Background:
cytoplasm
Synonyms:
Glycosyltransferase 1 domain-containing protein 1 (EC 2.4.-.-), GLT1D1
UniProt Protein Function:
GLT1D1: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Transferase; EC 2.4.-.-; Secreted, signal peptideChromosomal Location of Human Ortholog: 12q24.33Cellular Component: cytoplasm; extracellular regionMolecular Function: transferase activity, transferring glycosyl groupsBiological Process: metabolic process
