Glutaminase (GLS) Rabbit Polyclonal Antibody (CAB3885)
- SKU:
- CAB3885
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Glutaminase (GLS) Rabbit Polyclonal Antibody |
SKU: | CAB3885 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 610-669 of human Glutaminase (Glutaminase (GLS)) (NP_055720.3). |
Sequence: | KVNP FPKD RWNN TPMD EALH FGHH DVFK ILQE YQVQ YTPQ GDSD NGKE NQTV HKNL DGLL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | GAC; GAM; KGA; GLS1; AAD20; DEE71; GDPAG; CASGID; EIEE71; Glutaminase (GLS) |
Positive Sample: | U-251MG,NIH/3T3,Mouse brain,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, cytosol. |
Calculated MW: | 73kDa |
Observed MW: | 65-73kDa |
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2744 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |