The GLRA2 Polyclonal Antibody (CAB15673) is specifically designed for research involving the glycine receptor alpha 2 (GLRA2) protein. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GLRA2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal tool for studies in neuroscience and neurology research.The GLRA2 protein is a crucial component of the glycine receptor, a major inhibitory neurotransmitter receptor in the central nervous system. Dysfunction of the glycine receptor has been implicated in various neurological disorders, including hyperekplexia and other movement disorders.
Therefore, investigating the role of GLRA2 in neurotransmission and synaptic signaling is essential for understanding the pathophysiology of these conditions and developing potential therapeutic interventions.Overall, the GLRA2 Polyclonal Antibody is a valuable asset for researchers delving into the complexities of neurobiology and neurological disorders. Its high specificity and sensitivity make it a reliable tool for exploring the function and regulation of the GLRA2 protein in health and disease.
Product Name:
GLRA2 Rabbit Polyclonal Antibody
SKU:
CAB15673
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_002054.1).
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2742
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using GLRA2 antibody (CAB15673) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
