The GLP2 Polyclonal Antibody (CAB5009) is a rabbit monoclonal antibody intended for research involving GLP2, a peptide hormone that plays a crucial role in gastrointestinal function and energy metabolism. This antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds to the GLP2 protein, allowing for the detection and analysis of GLP2 levels in various cell types, making it ideal for studies in gastroenterology, metabolism, and endocrinology research.GLP2, also known as glucagon-like peptide 2, is a key regulator of intestinal growth and nutrient absorption, making it a potential target for therapeutic interventions in conditions such as short bowel syndrome and inflammatory bowel disease.
By studying the expression and function of GLP2, researchers can gain insights into its role in maintaining gut homeostasis and developing treatments for gastrointestinal disorders. Understanding the mechanisms of GLP2 action is essential for developing targeted therapies to improve digestive health and overall well-being.
Product Name:
GLP2 Rabbit Monoclonal Antibody
SKU:
CAB5009
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 81-180 of human GLP-2 (P01275).
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Purification Method:
Affinity purification
Gene ID:
2641
Clone Number:
ARC1143
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Confocal imaging of paraffin-embedded Rat pancreas tissue using GLP-2 Rabbit mAb (A5009, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007, dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 40x. Perform high pressure antigen retrieval with 0.01 M citrate buffer (pH 6.0) prior to IF staining.
