The GLO1 Rabbit Monoclonal Antibody (CAB4329) is a powerful tool for researchers studying the glyoxalase pathway, specifically focusing on the GLO1 enzyme. This antibody, derived from rabbit monoclonal cells, is highly specific and reactive with human samples, making it ideal for various research applications.GLO1 is a key enzyme in the glyoxalase system, responsible for detoxifying methylglyoxal, a toxic byproduct of glycolysis. Dysregulation of GLO1 has been implicated in various diseases, including diabetes, neurodegenerative disorders, and cancer. By targeting GLO1 with this antibody, researchers can investigate its role in these pathologies and potentially develop new therapeutic strategies.
This monoclonal antibody is validated for use in Western blotting, immunofluorescence, and immunohistochemistry applications, providing flexibility for researchers to study GLO1 expression and localization in different experimental systems. With its high specificity and sensitivity, the GLO1 Rabbit Monoclonal Antibody (CAB4329) is a valuable tool for advancing our understanding of the glyoxalase pathway and its implications in human health and disease.
Product Name:
GLO1 Rabbit Monoclonal Antibody
SKU:
CAB4329
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLO1 (Q04760).
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
Purification Method:
Affinity purification
Gene ID:
2739
Clone Number:
ARC0969
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GLO1 Rabbit mAb (CAB4329) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
