The GLO1 Polyclonal Antibody (CAB1932) is a powerful tool for research involving glyoxalase 1 (GLO1), an enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.GLO1 is a key player in cellular defense against oxidative stress and has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders.
By targeting GLO1 with this antibody, researchers can explore its role in these conditions and potentially develop new therapeutic strategies.Investigating the function and regulation of GLO1 with the CAB1932 antibody can provide valuable insights into cellular metabolism, stress response mechanisms, and disease pathways. It is a valuable tool for scientists working in biochemistry, molecular biology, and biomedical research.
Product Name:
GLO1 Rabbit Polyclonal Antibody
SKU:
CAB1932
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human GLO1 (NP_006699.2).
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
Purification Method:
Affinity purification
Gene ID:
2739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GLO1 Rabbit pAb (CAB1932) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
