GLIS3 Rabbit Polyclonal Antibody (CAB12166)
- SKU:
- CAB12166
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GLIS3 Rabbit Polyclonal Antibody |
SKU: | CAB12166 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 606-775 of human GLIS3 (NP_689842.3). |
Sequence: | DAGA ERFA PSAP SPHH ISPR RVPA PSSI LQRT QPPY TQQP SGSH LKSY QPET NSSF QPNG IHVH GFYG QLQK FCPP HYPD SQRI VPPV SSCS VVPS FEDC LVPT SMGQ ASFD VFHR AFST HSGI TVYD LPSS SSSL FGES LRSG AEDA TFLQ ISTV DRCP SQLS SVYT EG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NDH; ZNF515; GLIS3 |
Positive Sample: | Mouse ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 84kDa |
Observed MW: | 84kDa |
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
Purification Method: | Affinity purification |
Gene ID: | 169792 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |