GLI3 Rabbit Polyclonal Antibody (CAB15613)
- SKU:
- CAB15613
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GLI3 Rabbit Polyclonal Antibody |
SKU: | CAB15613 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 681-788 of human GLI3 (NP_000159.3). |
Sequence: | NTTS KREE CLQV KTVK AEKP MTSQ PSPG GQSS CSSQ QSPI SNYS NSGL ELPL TDGG SIGD LSAI DETP IMDS TIST ATTA LALQ ARRN PAGT KWME HVKL ERLK QVNG |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; GLI3 |
Positive Sample: | Mouse thymus,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | axoneme, ciliary base, ciliary tip, cilium, cytoplasm, cytosol, GLI-SUFU complex, nuclear speck, nucleolus, nucleoplasm, nucleus |
Calculated MW: | 170kDa |
Observed MW: | Refer to figures |
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
Purification Method: | Affinity purification |
Gene ID: | 2737 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |