Description
Product Name: | GLDC Polyclonal Antibody |
SKU: | CAB24541 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 580-749 of human GLDC (NP_000161.2). |
Sequence: | HPFV PLDQ AQGY QQLF RELE KDLC ELTG YDQV CFQP NSGA QGEY AGLA TIRA YLNQ KGEG HRTV CLIP KSAH GTNP ASAH MAGM KIQP VEVD KYGN IDAV HLKA MVDK HKEN LAAI MITY PSTN GVFE ENIS DVCD LIHQ HGGQ VYLD GANM NAQV GICR PGDF GSDV SH |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | GLDC; GCE; GCSP; HYGN1; glycine decarboxylase |
Positive Sample: | BeWo,Hep G2,U-251 MG (Low expression control),Mouse liver,Rat kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 112kDa |
Observed MW: | 113kDa |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Purification Method: | Affinity purification |
Gene ID: | 2731 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |