GLDC Rabbit Polyclonal Antibody (CAB9933)
- SKU:
- CAB9933
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GLDC Rabbit Polyclonal Antibody |
SKU: | CAB9933 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_000161.2). |
Sequence: | DSSS GGGD SAAA GASR LLER LLPR HDDF ARRH IGPG DKDQ REML QTLG LASI DELI EKTV PANI RLKR PLKM EDPV CENE ILAT LHAI SSKN QIWR SYIG MGYY NCSV PQTI LRNL LENS GWIT QYTP YQPE VSQG RLES LLNY QTMV CDIT GLDM ANAS LLDE GTAA AEAL QLCY RHNK RRKF LVDP RCHP QTIA VVQT RAKY TGVL TELK LPCE MDFS GKDV SGVL FQYP DTEG KVED FTEL VERA HQSG SLA |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | GCE; GCSP; HYGN1; GLDC |
Positive Sample: | HepG2,DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Purification Method: | Affinity purification |
Gene ID: | 2731 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |