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gL Antibody (PACO35082)

SKU:
PACO35082
Product Type:
Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€359

Description

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gL Antibody (PACO35082)

The GL Antibody (PAC035082) is a highly specific polyclonal antibody designed for research involving the GL protein, a crucial regulator of lipid metabolism and inflammation. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for investigations into the role of GL in various cellular processes.GL, also known as a key player in lipid metabolism pathways, has been implicated in the development of metabolic disorders such as obesity, diabetes, and cardiovascular diseases. By targeting the GL protein with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic targets.

Validated for use in Western blot applications, the GL Antibody enables researchers to detect and analyze the expression of GL in different cell types, allowing for detailed studies in the fields of metabolism, inflammation, and lipid biology. Its high specificity and sensitivity make it a valuable tool for advancing our understanding of the complex interplay between lipid metabolism and inflammatory processes.

Antibody Name:gL Antibody (PACO35082)
Antibody SKU:PACO35082
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Human cytomegalovirus
Immunogen:Recombinant Human cytomegalovirus Envelope glycoprotein L protein (31-278AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Synonyms:Envelope glycoprotein L (gL), gL
UniProt Protein Function:The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
UniProt Protein Details:
NCBI Summary:
UniProt Code:F5HCH8
NCBI GenInfo Identifier:52139280
NCBI Gene ID:3077416
NCBI Accession:YP_081555.1
UniProt Secondary Accession:F5HCH8
UniProt Related Accession:F5HCH8,Q71DN9
Molecular Weight:29.5 kDa
NCBI Full Name:envelope glycoprotein L
NCBI Synonym Full Names:
NCBI Official Symbol:UL115  
NCBI Official Synonym Symbols:
NCBI Protein Information:contains signal peptide; complexed with envelope glycoprotein H; involved in cell entry; involved in cell-to-cell spread
UniProt Protein Name:Envelope glycoprotein L
UniProt Synonym Protein Names:
Protein Family:Envelope glycoprotein
UniProt Gene Name:gL  
UniProt Entry Name:GL_HCMVM

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