The GKN1 Polyclonal Antibody (CAB13107) is a powerful tool for researchers studying GKN1, a protein involved in gastric mucosal defense and potential tumor suppression. This antibody, produced in rabbits, shows strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the GKN1 protein, researchers can easily visualize and analyze its expression in various cell types, making it an invaluable tool for studies in gastroenterology and cancer research.
GKN1, also known as gastrokine-1, has been shown to play a crucial role in protecting the stomach lining from damage and maintaining its integrity. Additionally, studies have suggested a potential tumor-suppressive role for GKN1 in various cancers, making it an interesting target for further investigation. Understanding the function and regulation of GKN1 could lead to new insights into gastric health and potential therapeutic strategies for gastrointestinal diseases and cancer treatment.
Product Name:
GKN1 Rabbit Polyclonal Antibody
SKU:
CAB13107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-185 of human GKN1 (NP_062563.3).
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.
Purification Method:
Affinity purification
Gene ID:
56287
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse stomach, using GKN1 Rabbit pAb (CAB13107) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
