The GKAP1 Polyclonal Antibody (PACO36418) is a valuable tool for researchers studying GKAP1, a protein involved in synaptic function and neuronal signaling. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the GKAP1 protein, researchers can detect and analyze its expression in various tissues and cell types, making it ideal for studies in neuroscience and neurobiology.GKAP1, also known as SAPAP1, plays a crucial role in the organization of synaptic structures and the regulation of synaptic transmission. Disruptions in GKAP1 function have been implicated in neurological disorders such as schizophrenia, autism, and intellectual disabilities.
Investigating the role of GKAP1 in these conditions can provide valuable insights into their underlying mechanisms and potential therapeutic targets.Overall, the GKAP1 Polyclonal Antibody is a powerful tool for studying the function of GKAP1 in neuronal signaling pathways, synaptic plasticity, and neurological disorders. Its high specificity and sensitivity make it an essential reagent for researchers seeking to advance our understanding of the complex mechanisms governing brain function.
Antibody Name:
GKAP1 Antibody (PACO36418)
Antibody SKU:
PACO36418
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human G kinase-anchoring protein 1 protein (21-366AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO36418 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human cervical cancer using PACO36418 at dilution of 1:100.
Background:
Golgi apparatus, signal transduction
Synonyms:
G kinase-anchoring protein 1 (cGMP-dependent protein kinase-anchoring protein of 42 kDa), GKAP1, GKAP42
UniProt Protein Function:
GKAP1: a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 9q21.32Cellular Component: Golgi apparatusBiological Process: signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
G kinase-anchoring protein 1; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; protein kinase anchoring protein GKAP42
UniProt Protein Name:
G kinase-anchoring protein 1
UniProt Synonym Protein Names:
cGMP-dependent protein kinase-anchoring protein of 42 kDa
