GK/GK3P Antibody (PACO00856)
- SKU:
- PACO00856
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GK/GK3P Antibody (PACO00856)
The GK/GK3P Polyclonal Antibody (PACO00856) is a valuable tool for researchers studying the GK/GK3P protein, involved in immune regulation and immune response modulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for Western blot applications.The GK/GK3P protein is known for its role in immune homeostasis, regulating inflammation and inhibiting allergic reactions. Its involvement in immune modulation makes it a promising target for research in various areas, including cancer, autoimmune disorders, and chronic inflammatory conditions.
By detecting and analyzing the GK/GK3P protein in different cell types, this antibody is essential for advancing studies in immunology and cancer research.Understanding the function of the GK/GK3P protein is essential for developing treatments that manipulate immune responses in disease contexts. The GK/GK3P Polyclonal Antibody provides researchers with a reliable tool to investigate the role of the GK/GK3P protein in immune regulation and its potential as a therapeutic target.
| Antibody Name: | GK/GK3P Antibody |
| Antibody SKU: | PACO00856 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the N-terminal region of human GK1/3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GK; Glycerol kinase; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase; GK3P; GKP3; GKTB; Putative glycerol kinase 3; GK 3; Glycerokinase 3; ATP:glycerol 3-phosphotransferase 3; Glycerol kinase; testis specific 1 |
| UniProt Protein Function: | GLPK: Key enzyme in the regulation of glycerol uptake and metabolism. Defects in GK are the cause of GK deficiency (GKD). This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only. Belongs to the FGGY kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.7.1.30; Lipid Metabolism - glycerolipid; Mitochondrial; Kinase, other Chromosomal Location of Human Ortholog: Xp21.3 Cellular Component: mitochondrial outer membrane; cytosol; nucleus Molecular Function:glycerol kinase activity; protein binding; ATP binding Biological Process: triacylglycerol metabolic process; glycerol metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; glucose homeostasis; phosphorylation; glycerol-3-phosphate biosynthetic process; glycerol catabolic process Disease: Glycerol Kinase Deficiency |
| NCBI Summary: | The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | P32189 |
| NCBI GenInfo Identifier: | 205830913 |
| NCBI Gene ID: | 2710 |
| NCBI Accession: | P32189.3 |
| UniProt Secondary Accession: | P32189,Q6IQ27, Q8IVR5, Q9UMP0, Q9UMP1, A6NJP5, B2R833 |
| UniProt Related Accession: | P32189 |
| Molecular Weight: | 58,141 Da |
| NCBI Full Name: | Glycerol kinase |
| NCBI Synonym Full Names: | glycerol kinase |
| NCBI Official Symbol: | GKÂ Â |
| NCBI Official Synonym Symbols: | GK1; GKDÂ Â |
| NCBI Protein Information: | glycerol kinase; ATP:glycerol 3-phosphotransferase; glycerokinase |
| UniProt Protein Name: | Glycerol kinase |
| UniProt Synonym Protein Names: | ATP:glycerol 3-phosphotransferase |
| Protein Family: | Glycerol kinase |
| UniProt Gene Name: | GKÂ Â |
| UniProt Entry Name: | GLPK_HUMAN |
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