The GJD2 Polyclonal Antibody (CAB2883) is a valuable tool for researchers studying GJD2, a protein involved in cell-cell communication in the brain and nervous system. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.GJD2, also known as Connexin 36, is a member of the gap junction protein family and is essential for the synchronization of neuronal activity. Dysfunction of GJD2 has been linked to neurological disorders such as epilepsy and migraine.
By targeting GJD2 with this antibody, researchers can investigate its role in neurological function and pathology.The GJD2 Polyclonal Antibody is a valuable asset for studies in neuroscience and neurology, providing researchers with a reliable tool to explore the function and regulation of GJD2 in the brain and nervous system. Its use can potentially lead to a deeper understanding of neurological disorders and the development of novel therapeutic strategies.
Product Name:
GJD2 Rabbit Polyclonal Antibody
SKU:
CAB2883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 99-197 of human GJD2 (NP_065711.1).
Cell junction, Cell membrane, Multi-pass membrane protein, gap junction.
Calculated MW:
36kDa
Observed MW:
37kDa
This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion.
Purification Method:
Affinity purification
Gene ID:
57369
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GJD2 antibody (CAB2883) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
