The GJC3 Polyclonal Antibody (PACO04132) is a high-quality antibody designed for research involving GJC3, a protein involved in cell-cell communication and the formation of gap junctions. The antibody is raised in rabbits and is highly reactive with human samples, making it an ideal tool for studying GJC3 in various cell types.Gap junctions, formed by proteins like GJC3, play a crucial role in facilitating direct communication between adjacent cells. This communication is essential for coordinating cellular activities and maintaining tissue homeostasis. The GJC3 antibody is validated for use in Western blot applications, enabling researchers to detect and analyze GJC3 expression levels in different experimental conditions.
With its key role in cell communication, GJC3 is of interest in various fields of research, including developmental biology, neuroscience, and cancer biology. By studying GJC3, researchers can gain insights into how cells communicate with each other and how disruptions in this process contribute to disease states. The GJC3 Polyclonal Antibody provides a valuable tool for investigating the function of GJC3 and its implications in various physiological and pathological processes.
Antibody Name:
GJC3 Antibody
Antibody SKU:
PACO04132
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Connexin 31.3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GJC3; GJE1; Gap junction gamma-3 protein; Connexin-30.2; Cx30.2; Connexin-31.3; Cx31.3; Gap junction epsilon-1 protein
UniProt Protein Function:
GJC3: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7q22.1
UniProt Protein Details:
NCBI Summary:
This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010]
