The GJC1 Polyclonal Antibody (CAB7053) is a essential tool for researchers studying gap junction protein C-1 (GJC1), a vital component in cell-to-cell communication processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting GJC1 in human samples, making it suitable for use in Western blot applications. By binding to the GJC1 protein, this antibody enables researchers to accurately analyze and study the expression and function of GJC1 in various cell types.GJC1, also known as connexin-45, plays a crucial role in the formation of gap junction channels that allow for the exchange of ions, metabolites, and signaling molecules between adjacent cells. Dysregulation of GJC1 has been linked to various diseases, including cardiac disorders and neurological conditions.
Therefore, investigating the role of GJC1 in cell communication pathways is essential for understanding its impact on health and disease.The GJC1 Polyclonal Antibody is a valuable tool for researchers exploring the physiological and pathological functions of GJC1 in different biological contexts. Its reliability and specificity make it an indispensable resource for studies in cell biology, neuroscience, and cardiovascular research. By using this antibody, researchers can gain valuable insights into the role of GJC1 in cellular communication and potentially identify novel therapeutic targets for associated disorders.
Product Name:
GJC1 Rabbit Polyclonal Antibody
SKU:
CAB7053
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 247-396 of human GJC1 (NP_005488.2).
Cell junction, Cell membrane, Multi-pass membrane protein, gap junction.
Calculated MW:
45kDa
Observed MW:
45kDa
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.
Purification Method:
Affinity purification
Gene ID:
10052
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GJC1 antibody (CAB7053) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
