GJA9 Antibody (PACO18601)
- SKU:
- PACO18601
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
GJA9 Antibody (PACO18601)
The GJA9 Antibody (PAC018601) offered by Assay Genie is a high-quality polyclonal antibody designed for research involving GJA9, a protein associated with gap junction channels. This antibody, raised in rabbits, is suitable for use in various applications such as immunofluorescence, immunohistochemistry, and flow cytometry, making it a versatile tool for studying cellular communication and signaling pathways.GJA9, also known as connexin 40, is a critical component of gap junction channels that facilitate direct cell-to-cell communication through the exchange of small molecules and ions. This communication plays a vital role in various physiological processes, including cardiac function, neurodevelopment, and cell differentiation.
The GJA9 Antibody enables the detection and analysis of GJA9 protein levels in different cell types, providing valuable insights into its function and localization within tissues.Research into gap junction channels and connexin proteins like GJA9 is essential for understanding the mechanisms of intercellular communication and its impact on cellular signaling pathways. The GJA9 Antibody from Assay Genie offers researchers a reliable tool to investigate the role of GJA9 in various biological processes, making it a valuable asset for studies in cell biology, neuroscience, and cardiovascular research.
| Antibody Name: | GJA9 Antibody (PACO18601) |
| Antibody SKU: | PACO18601 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human GJA9 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane: Human placenta tissue, Primary antibody: PACO18601(GJA9 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. |
| Background: | Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits. |
| Synonyms: | gap junction protein, α 9, 59kDa |
| UniProt Protein Function: | GJA9: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p34 Cellular Component: connexon complex; integral to membrane Biological Process: cell communication |
| NCBI Summary: | Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P57773 |
| NCBI GenInfo Identifier: | 50403749 |
| NCBI Gene ID: | 81025 |
| NCBI Accession: | P57773.2 |
| UniProt Secondary Accession: | P57773,Q5TA63, Q96KG0, B2R722, B3KVQ2, |
| UniProt Related Accession: | P57773 |
| Molecular Weight: | 515 |
| NCBI Full Name: | Gap junction alpha-9 protein |
| NCBI Synonym Full Names: | gap junction protein, alpha 9, 59kDa |
| NCBI Official Symbol: | GJA9Â Â |
| NCBI Official Synonym Symbols: | CX58; CX59; GJA10Â Â |
| NCBI Protein Information: | gap junction alpha-9 protein; connexin 59; connexin-58; gap junction alpha 10 |
| UniProt Protein Name: | Gap junction alpha-9 protein |
| UniProt Synonym Protein Names: | Connexin-58; Cx58; Connexin-59; Cx59; Gap junction alpha-10 protein |
| Protein Family: | Gap junction alpha-9 protein |
| UniProt Gene Name: | GJA9Â Â |
| UniProt Entry Name: | CXA9_HUMAN |
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