The GJA5 Polyclonal Antibody (CAB13494) is a powerful tool for researchers studying GJA5, a key protein involved in cell communication and heart function. This antibody, produced in rabbits, is highly specific to human samples and has been rigorously validated for use in Western blotting applications. By binding to the GJA5 protein, it allows for the accurate detection and analysis of GJA5 in various cell types.GJA5, also known as Connexin 40, plays a critical role in the electrical conduction system of the heart, facilitating the transmission of signals between cardiac cells. Dysregulation of GJA5 has been linked to various cardiac disorders, including arrhythmias and conduction abnormalities.
Therefore, investigating the function and expression of GJA5 is essential for advancing our understanding of cardiac physiology and pathology.Researchers in the fields of cardiology, physiology, and molecular biology will find the GJA5 Polyclonal Antibody to be an invaluable tool for their studies. By utilizing this antibody, scientists can gain insights into the role of GJA5 in heart health and disease, potentially leading to the development of novel therapeutic strategies for cardiac conditions.
Product Name:
GJA5 Rabbit Polyclonal Antibody
SKU:
CAB13494
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 229-358 of human GJA5 (NP_859054.1).
Cell junction, Cell membrane, Multi-pass membrane protein, gap junction.
Calculated MW:
40kDa
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.
Purification Method:
Affinity purification
Gene ID:
2702
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using GJA5 antibody (CAB13494). Blue: DAPI for nuclear staining.
