The GJA4 Polyclonal Antibody (CAB2529) is a valuable tool for researchers studying GJA4, a gene encoding the connexin 37 protein. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the GJA4 protein, this antibody allows for the detection and analysis of connexin 37 in various cell types, making it ideal for investigations in cardiovascular and vascular biology.Connexin 37 is a crucial component of gap junction channels, which play a key role in intercellular communication in the vascular system. Dysregulation of connexin 37 has been implicated in various cardiovascular diseases, making it a promising target for research.
By studying the function and regulation of GJA4, researchers can gain insights into the mechanisms underlying vascular development, blood flow regulation, and vascular dysfunction.Overall, the GJA4 Polyclonal Antibody (CAB2529) offers researchers a reliable tool for exploring the role of connexin 37 in cardiovascular health and disease. Its specificity, sensitivity, and versatility make it a valuable asset for studies aiming to unravel the complexities of vascular biology.
Product Name:
GJA4 Rabbit Polyclonal Antibody
SKU:
CAB2529
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 229-333 of human GJA4 (NP_002051.2).
Cell junction, Cell membrane, Multi-pass membrane protein, gap junction.
Calculated MW:
37kDa
Observed MW:
37kDa/
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
Purification Method:
Affinity purification
Gene ID:
2701
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver using GJA4 Rabbit pAb(CAB2529) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
