GJA1 Rabbit Polyclonal Antibody (CAB11752)
- SKU:
- CAB11752
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GJA1 Rabbit Polyclonal Antibody |
SKU: | CAB11752 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 233-382 of human Connexin 43 (NP_000156.1). |
Sequence: | FKGV KDRV KGKS DPYH ATSG ALSP AKDC GSQK YAYF NGCS SPTA PLSP MSPP GYKL VTGD RNNS SCRN YNKQ ASEQ NWAN YSAE QNRM GQAG STIS NSHA QPFD FPDD NQNS KKLA AGHE LQPL AIVD QRPS SRAS SRAS SRPR PDDL EI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HSS; CMDR; CX43; EKVP; GJAL; ODDD; AVSD3; EKVP3; HLHS1; PPKCA; Connexin 43 |
Positive Sample: | HeLa,Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Endoplasmic reticulum, Multi-pass membrane protein, gap junction. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.
Purification Method: | Affinity purification |
Gene ID: | 2697 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |