The Ko-validated GIT1 Polyclonal Antibody (CAB15437) is a key tool for researchers studying the GIT1 protein, an important regulator of cell signaling pathways involved in cell growth and migration. This high-quality antibody, generated in rabbits, is specifically designed for use in Western blot applications and has been validated for its reactivity with human samples.The GIT1 protein, also known as G protein-coupled receptor kinase interactor 1, is known to play a crucial role in various cellular processes such as cell adhesion, cytoskeletal rearrangement, and cell motility. It is particularly involved in the regulation of focal adhesion dynamics and integrin signaling, making it a valuable target for research in cancer biology, neurobiology, and cell biology.
By using the Ko-validated GIT1 Polyclonal Antibody, researchers can confidently detect and analyze GIT1 protein expression in a variety of cell types, allowing for a deeper understanding of its functions and potential implications in disease. This antibody is a valuable tool for studies aiming to unravel the complex mechanisms of cell signaling and may contribute to the development of novel therapeutic strategies targeting GIT1-related pathways.
Product Name:
[KO Validated] GIT1 Rabbit Polyclonal Antibody
SKU:
CAB15437
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-640 of human GIT1 (NP_054749.2).
Enables gamma-tubulin binding activity. Involved in positive regulation of microtubule nucleation and regulation of cytokinesis. Located in several cellular components, including focal adhesion; microtubule cytoskeleton; and mitochondrion. Implicated in attention deficit hyperactivity disorder. Biomarker of Huntington's disease.
Purification Method:
Affinity purification
Gene ID:
28964
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] GIT1 Rabbit pAb (CAB15437) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
