GIPR Rabbit Polyclonal Antibody (CAB9816)
- SKU:
- CAB9816
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GIPR Rabbit Polyclonal Antibody |
SKU: | CAB9816 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1). |
Sequence: | RAET GSKG QTAG ELYQ RWER YRRE CQET LAAA EPPS GLAC NGSF DMYV CWDY AAPN ATAR ASCP WYLP WHHH VAAG FVLR QCGS DGQW GLWR DHTQ CENP EKNE AFLD QRLI LERL Q |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PGQTL2; GIPR |
Positive Sample: | K-562,Mouse liver,Rat heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 53kDa |
Observed MW: | 45kDa |
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Purification Method: | Affinity purification |
Gene ID: | 2696 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |