The Gins2 Polyclonal Antibody (CAB9172) is a vital tool for researchers studying Gins2, a key protein involved in cellular energy metabolism and mitochondrial function. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the Gins2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in the fields of metabolism, energy production, and cellular respiration.Gins2, also known as GINS complex subunit 2, is a critical component of the GINS complex that functions in DNA replication and repair processes. Its role in maintaining genomic stability and regulating cell proliferation underscores its importance in cell biology and cancer research.
By understanding the function and regulation of Gins2, researchers can uncover potential therapeutic targets for cancer treatment and develop strategies for combating diseases associated with aberrant cell division.Overall, the Gins2 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of Gins2 in cellular metabolism, DNA replication, and cancer development. Its high specificity and sensitivity make it a valuable asset for studies aiming to elucidate the molecular mechanisms underlying these biological processes.
Product Name:
GINS2 Rabbit Polyclonal Antibody
SKU:
CAB9172
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human GINS2 (NP_057179.1).
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.
Purification Method:
Affinity purification
Gene ID:
51659
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GINS2 antibody (CAB9172) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
